Headache

Diagnostic test accuracy of jolt accentuation for headache in acute meningitis in the emergency setting

Abstract Background Meningitis is inflammation of the meninges, the layers that protect the brain and spinal cord. Acute meningitis is an emergent disease that develops over the course of hours to several days. Delay in treatment can lead to serious outcomes. Inflammation of the meninges is assessed by analysing cerebrospinal fluid. Identifying the pathogen in […]

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Psychological therapies for the prevention of migraine in adults

Abstract Background Migraine is a common neurological problem associated with the highest burden amongst neurological conditions in terms of years lived with disability. Medications can be used as prophylaxis or rescue medicines, but are costly and not always effective. A range of psychological interventions have been developed to manage migraine. Objectives The objective was to […]

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Psychological therapies for the prevention of migraine in adults

Abstract Background Migraine is a common neurological problem associated with the highest burden amongst neurological conditions in terms of years lived with disability. Medications can be used as prophylaxis or rescue medicines, but are costly and not always effective. A range of psychological interventions have been developed to manage migraine. Objectives The objective was to […]

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Botulinum toxins for the prevention of migraine in adults

Abstract Background Migraine occurs in around 15% of adults and is ranked as the seventh most disabling disease amongst all diseases globally. Despite the available treatments many people suffer prolonged and frequent attacks which have a major impact on their quality of life. Chronic migraine is defined as 15 or more days of headache per […]

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Needle gauge and tip designs for preventing post-dural puncture headache (PDPH)

Abstract Background Post-dural puncture headache (PDPH) is one of the most common complications of diagnostic and therapeutic lumbar punctures. PDPH is defined as any headache occurring after a lumbar puncture that worsens within 15 minutes of sitting or standing and is relieved within 15 minutes of the patient lying down. Researchers have suggested many types […]

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Aspirin for acute treatment of episodic tension-type headache in adults

Abstract Background Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache per month), frequent episodic TTH (two to 14 headache days per month), and chronic TTH (15 headache days per month or more). Aspirin is one of a number of analgesics suggested for […]

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Ketoprofen for episodic tension-type headache in adults

Abstract Background Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache day per month), frequent episodic TTH (2 to 14 headache days per month), and chronic TTH (15 headache days a month or more). Ketoprofen is one of a number of analgesics suggested […]

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Paracetamol (acetaminophen) for acute treatment of episodic tension-type headache in adults

Abstract Background Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache per month), frequent episodic TTH (two to 14 headaches per month), and chronic TTH (15 headache days a month or more). Paracetamol (acetaminophen) is one of a number of analgesics suggested for […]

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Sumatriptan plus naproxen for acute migraine attacks in adults

Abstract Background This is an updated version of the original Cochrane review published in October 2013 on ‘Sumatriptan plus naproxen for acute migraine attacks in adults’. Migraine is a common disabling condition and a burden for the individual, health services, and society. It affects two to three times more women than men, and is most […]

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Drugs for the acute treatment of migraine in children and adolescents

Abstract Background Numerous medications are available for the acute treatment of migraine in adults, and some have now been approved for use in children and adolescents in the ambulatory setting. A systematic review of acute treatment of migraine medication trials in children and adolescents will help clinicians make evidence-informed management choices. Objectives To assess the […]

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