Medical care

Couple and family therapies for post‐traumatic stress disorder (PTSD)

Abstract Background Post‐traumatic stress disorder (PTSD) refers to an anxiety or trauma‐ and stressor‐related disorder that is linked to personal or vicarious exposure to traumatic events. PTSD is associated with a range of adverse individual outcomes (e.g. poor health, suicidality) and significant interpersonal problems which include difficulties in intimate and family relationships. A range of […]

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Individual recovery expectations and prognosis of outcomes in non‐specific low back pain: prognostic factor review

Abstract Background Low back pain is costly and disabling. Prognostic factor evidence can help healthcare providers and patients understand likely prognosis, inform the development of prediction models to identify subgroups, and may inform new treatment strategies. Recent studies have suggested that people who have poor expectations for recovery experience more back pain disability, but study […]

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Indomethacin for intracranial hypertension secondary to severe traumatic brain injury in adults

Abstract Background Among people who have suffered a traumatic brain injury, increased intracranial pressure continues to be a major cause of early death; it is estimated that about 11 people per 100 with traumatic brain injury die. Indomethacin (also known as indometacin) is a powerful cerebral vasoconstrictor that can reduce intracranial pressure and, ultimately, restore […]

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Present-centered therapy (PCT) for post-traumatic stress disorder (PTSD) in adults

Abstract Background Present‐centered therapy (PCT) is a non‐trauma, manualized psychotherapy for adults with post‐traumatic stress disorder (PTSD). PCT was originally designed as a treatment comparator in trials evaluating the effectiveness of trauma‐focused cognitive‐behavioral therapy (TF‐CBT). Recent trials have indicated that PCT may be an effective treatment option for PTSD and that patients may drop out […]

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Interventions for eye movement disorders due to acquired brain injury

Abstract Background Acquired brain injury can cause eye movement disorders which may include: strabismus, gaze deficits and nystagmus, causing visual symptoms of double, blurred or ‘juddery’ vision and reading difficulties. A wide range of interventions exist that have potential to alleviate or ameliorate these symptoms. There is a need to evaluate the effectiveness of these […]

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Elevation of the head during intensive care management in people with severe traumatic brain injury

Abstract Background Traumatic brain injury (TBI) is a major public health problem and a fundamental cause of morbidity and mortality worldwide. The burden of TBI disproportionately affects low- and middle-income countries. Intracranial hypertension is the most frequent cause of death and disability in brain-injured people. Special interventions in the intensive care unit are required to […]

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Interventions for managing skeletal muscle spasticity following traumatic brain injury

Abstract Background Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness, reduced range of movement, broken skin and pain. Treatments for spasticity include a range of pharmacological and non-pharmacological interventions, often used in combination. Management of spasticity following TBI varies from other […]

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Antifibrinolytic drugs for acute traumatic injury

Abstract Background Uncontrolled bleeding is an important cause of death in trauma victims. Antifibrinolytic treatment has been shown to reduce blood loss following surgery and may also be effective in reducing blood loss following trauma. Objectives To assess the effect of antifibrinolytic drugs in patients with acute traumatic injury. Search methods We ran the most […]

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Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures

Abstract Background Basilar skull fractures predispose patients to meningitis because of the possible direct contact of bacteria in the paranasal sinuses, nasopharynx or middle ear with the central nervous system (CNS). Cerebrospinal fluid (CSF) leakage has been associated with a greater risk of contracting meningitis. Antibiotics are often given prophylactically, although their role in preventing […]

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Pharmacological interventions for preventing post-traumatic stress disorder (PTSD)

Abstract Background Post-traumatic stress disorder (PTSD) is a debilitating disorder which, after a sufficient delay, may be diagnosed amongst individuals who respond with intense fear, helplessness or horror to traumatic events. There is some evidence that the use of pharmacological interventions immediately after exposure to trauma may reduce the risk of developing of PTSD. Objectives […]

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