Dementia and cognitive impairment

Subjective barriers to prevent wandering of cognitively impaired people

Abstract Background People with dementia often wander, at times putting themselves at risk and presenting challenges to carers and institutional staff. Traditional interventions to prevent wandering include restraint, drugs and locked doors. Cognitively impaired people may respond to environmental stimuli (sounds, images, smells) in ways distinct from healthy people. This has led to trials of […]

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Lecithin for dementia and cognitive impairment

Abstract Background Alzheimer’s disease sufferers have been found to lack the enzyme responsible for converting choline into acetylcholine within the brain. Lecithin is a major dietary source of choline, so extra consumption may reduce the progression of dementia. Objectives To determine the efficacy of lecithin in the treatment of dementia or cognitive impairment. Search methods […]

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Aspirin for vascular dementia

Abstract Background Aspirin is widely prescribed for patients with a diagnosis of vascular dementia. In a survey of UK geriatricians and psychiatrists 80% of patients with clinical diagnoses of vascular dementia were prescribed aspirin. However, a number of queries remain unanswered. Is there convincing evidence that aspirin benefits patients with vascular dementia? Does aspirin affect […]

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Hydergine for dementia

Abstract Background Currently hydergine is used almost exclusively for treating patients with either dementia, or ‘age-related’ cognitive symptoms. Since the early 1980s there have been over a dozen more clinical trials, yet hydergine’s efficacy remains uncertain. Although previous reviews offer generally favourable support for hydergine’s efficacy, they were, however, limited by a bias with respect […]

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