Neuro child

Vitamin K prior to preterm birth for preventing neonatal periventricular haemorrhage

Abstract Background Preterm infants are at risk of periventricular haemorrhage (PVH). This can be a sign of brain damage that might lead to neurodevelopmental abnormalities, including cerebral palsy. It has been suggested that vitamin K might improve coagulation in preterm infants and thereby decrease the risk of PVH. Objectives To assess the effects of vitamin […]

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Speech and language therapy to improve the communication skills of children with cerebral palsy

Abstract Background The production of speech, language and gesture for communication is often affected by cerebral palsy. Communication difficulties associated with cerebral palsy can be multifactorial, arising from motor, intellectual and sensory impairments. Children with this diagnosis can experience mild to severe difficulties in expressing themselves. They are often referred to speech and language therapy […]

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Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage

Abstract Background Preterm infants are at risk of periventricular haemorrhage (PVH). Phenobarbital might prevent ischaemic injury or reduce fluctuations in blood pressure and blood flow in the brain. Objectives To assess the benefits and harms of giving phenobarbital to women at risk of imminent very preterm birth with the primary aim of preventing PVH in […]

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High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma

Abstract Background Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Prognosis for patients with metastatic disease has not improved significantly in the past decades. High-dose chemotherapy (HDC) seems to be an attractive option to treat minimal residual disease in metastatic rhabdomyosarcoma patients. Objectives The objective of the review was to assess the effectiveness […]

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Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral palsy

Abstract Background Cerebral palsy (CP) is “a group of permanent disorders of the development of movement and posture causing activity limitation(s) that are attributed to non-progressive disturbance that occurred in the developing fetal or infant brain” (Rosenbaum 2007, p.9). The spastic motor type is the most common form of CP. Therapeutic management may include splinting/casting, […]

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Intervention for dysarthria associated with acquired brain injury in children and adolescents

Abstract Background The term ‘acquired brain injury’ (ABI) incorporates a range of aetiologies including cerebrovascular accident, brain tumour and traumatic brain injury. ABI is a common cause of disability in the paediatric population, and dysarthria is a common and often persistent sequelae associated with ABI in children. Objectives To assess the efficacy of intervention delivered […]

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Personal assistance for children and adolescents (0-18) with physical impairments

Abstract Background There is a high and increasing prevalence of impairments among children and adolescents in the West. Many countries offer personal assistance in the form of individualised support for people living in the community by a paid assistant other than a healthcare professional for at least 20 hours per week. Objectives To assess the […]

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Personal assistance for children and adolescents (0-18) with intellectual impairments

Abstract Background There is a high and increasing prevalence of intellectual impairments among children and adolescents in the West. Many countries offer personal assistance in the form of individualised support for people living in the community by a paid assistant other than a healthcare professional for at least 20 hours per week. Objectives To assess […]

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Personal assistance for children and adolescents (0-18) with both physical and intellectual impairments

Abstract Background There is a high and increasing prevalence of impairments among children and adolescents in the West. Many countries offer personal assistance in the form of individualised support for people living in the community by a paid assistant other than a healthcare professional for at least 20 hours per week. Objectives To assess the […]

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Intraventricular streptokinase after intraventricular hemorrhage in newborn infants

Abstract Background Hydrocephalus following intraventricular hemorrhage (IVH) is still one of the most serious complications of premature birth. Ventriculoperitoneal shunt surgery cannot be carried out early and permanent dependence on a shunt is associated with several serious complications. Streptokinase could be useful in the treatment of post-hemorrhagic hydrocephalus. This form of therapy is based on […]

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