Alcohol

Alcoholics Anonymous and other 12‐step programs for alcohol use disorder

Abstract Background Alcohol use disorder (AUD) confers a prodigious burden of disease, disability, premature mortality, and high economic costs from lost productivity, accidents, violence, incarceration, and increased healthcare utilization. For over 80 years, Alcoholics Anonymous (AA) has been a widespread AUD recovery organization, with millions of members and treatment free at the point of access, […]

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Family‐based prevention programmes for alcohol use in young people

Abstract Background Alcohol use in young people is a risk factor for a range of short‐ and long‐term harms and is a cause of concern for health services, policy‐makers, youth workers, teachers, and parents. Objectives To assess the effectiveness of universal, selective, and indicated family‐based prevention programmes in preventing alcohol use or problem drinking in […]

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Baclofen for alcohol use disorder

Abstract Background Alcohol use disorder (AUD) and alcohol‐related impairments belong to the most widespread psychiatric disorders leading to specific psychophysical, affective and cognitive symptoms and consequences for psychosocial well‐being and health. Alcohol consumption is increasingly becoming a problem in many developing regions and AUD prevalence is estimated at 4.1% worldwide, with highest prevalence in European […]

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Personalised digital interventions for reducing hazardous and harmful alcohol consumption in community-dwelling populations

Abstract Background Excessive alcohol use contributes significantly to physical and psychological illness, injury and death, and a wide array of social harm in all age groups. A proven strategy for reducing excessive alcohol consumption levels is to offer a brief conversation-based intervention in primary care settings, but more recent technological innovations have enabled people to […]

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Motivational interviewing for alcohol misuse in young adults

bstract Background Alcohol use and misuse in young people is a major risk behaviour for mortality and morbidity. Motivational interviewing (MI) is a popular technique for addressing excessive drinking in young adults. Objectives To assess the effects of motivational interviewing (MI) interventions for preventing alcohol misuse and alcohol-related problems in young adults. Search methods We […]

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Pharmacotherapy for anxiety and comorbid alcohol use disorders

Abstract Background Anxiety disorders are a potentially disabling group of disorders that frequently co-occur with alcohol use disorders. Comorbid anxiety and alcohol use disorders are associated with poorer outcomes, and are difficult to treat with standard psychosocial interventions. In addition, improved understanding of the biological basis of the conditions has contributed to a growing interest […]

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Psychosocial interventions to reduce alcohol consumption in concurrent problem alcohol and illicit drug users

Abstract Background Problem alcohol use is common among illicit drug users and is associated with adverse health outcomes. It is also an important factor contributing to a poor prognosis among drug users with hepatitis C virus (HCV) as it impacts on progression to hepatic cirrhosis or opiate overdose in opioid users. Objectives To assess the […]

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Restricting or banning alcohol advertising to reduce alcohol consumption in adults and adolescents

Abstract Background Alcohol is estimated to be the fifth leading risk factor for global disability-adjusted life years. Restricting or banning alcohol advertising may reduce exposure to the risk posed by alcohol at the individual and general population level. To date, no systematic review has evaluated the effectiveness, possible harms and cost-effectiveness of this intervention. Objectives […]

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Anticonvulsants for alcohol dependence

Abstract Background Alcohol dependence is a major public health problem that is characterised by recidivism and a host of medical and psychosocial complications. Besides psychosocial interventions, different pharmacological interventions have been or currently are under investigation through Cochrane systematic reviews. Objectives The primary aim of the review is to assess the benefits/risks of anticonvulsants for […]

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Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Abstract Background Autopsy studies suggest that Wernicke-Korsakoff syndrome (WKS) is not a rare disorder, particularly in individuals who abuse alcohol. Thiamine has been established as the treatment of choice for over 50 years, but uncertainty remains about appropriate dosage and duration. Current practice guidelines are based on case reports and clinical experience. This is an […]

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