Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid antibodies
Abstract Background Antiphospholipid syndrome (APS) is an autoimmune disease characterised by the presence ofantiphospholipid (aPL) antibodies that have prothrombotic activity. Antiphospholipidantibodies are associated with an increased risk of pregnancy complications (recurrent miscarriage, premature birth, intrauterine growth retardation) and thrombotic events (both arterial and venous). The most common thrombotic events include brain ischaemia (stroke or transient […]
Interventions for the management of oral ulcers in Behçet’s disease
Abstract Background Behçet’s disease is a chronic inflammatory vasculitis that can affect multiple systems. Mucocutaneous involvement is common, as is the involvement of many other systems such as the central nervous system and skin. Behç̧et’s disease can cause significant morbidity, such as loss of sight, and can be life threatening. The frequency of oral ulceration […]
Pharmacotherapy for Behcet’s syndrome
Abstract Background Behcet’s syndrome is a multisystemic disorder presenting with recurrent oral and genital ulcerations as well as ocular involvement. Treatment of Behcet’s syndrome is symptomatic and empirical. Objectives To determine the effects of available pharmacological interventions in treating the different clinical features of Behcet’s syndrome. Search methods We searched the Cochrane Musculoskeletal Group’s trials […]