Migrane

Botulinum toxins for the prevention of migraine in adults

Abstract Background Migraine occurs in around 15% of adults and is ranked as the seventh most disabling disease amongst all diseases globally. Despite the available treatments many people suffer prolonged and frequent attacks which have a major impact on their quality of life. Chronic migraine is defined as 15 or more days of headache per […]

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Needle gauge and tip designs for preventing post-dural puncture headache (PDPH)

Abstract Background Post-dural puncture headache (PDPH) is one of the most common complications of diagnostic and therapeutic lumbar punctures. PDPH is defined as any headache occurring after a lumbar puncture that worsens within 15 minutes of sitting or standing and is relieved within 15 minutes of the patient lying down. Researchers have suggested many types […]

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Sumatriptan plus naproxen for acute migraine attacks in adults

Abstract Background This is an updated version of the original Cochrane review published in October 2013 on ‘Sumatriptan plus naproxen for acute migraine attacks in adults’. Migraine is a common disabling condition and a burden for the individual, health services, and society. It affects two to three times more women than men, and is most […]

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Drugs for the acute treatment of migraine in children and adolescents

Abstract Background Numerous medications are available for the acute treatment of migraine in adults, and some have now been approved for use in children and adolescents in the ambulatory setting. A systematic review of acute treatment of migraine medication trials in children and adolescents will help clinicians make evidence-informed management choices. Objectives To assess the […]

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Acupuncture for tension-type headache

Abstract Background Acupuncture is often used for prevention of tension-type headache but its effectiveness is still controversial. This is an update of our Cochrane review originally published in Issue 1, 2009 ofThe Cochrane Library. Objectives To investigate whether acupuncture is a) more effective than no prophylactic treatment/routine care only; b) more effective than ‘sham’ (placebo) […]

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Normobaric and hyperbaric oxygen therapy for migraine and cluster headache

Abstract Background Migraine and cluster headaches are severe and disabling. Migraine affects up to 18% of women, while cluster headaches are much less common (0.2% of the population). A number of acute and prophylactic therapies are available. Hyperbaric oxygen therapy (HBOT) is the therapeutic administration of 100% oxygen at environmental pressures greater than one atmosphere, […]

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Pharmacological agents for the prevention of vestibular migraine

Abstract Background Vestibular migraine is a common cause of episodic vertigo. Many preventive treatments have been proposed for this condition, including calcium antagonists, beta-blockers, antidepressants, anticonvulsants, selective 5-HT1 agonists, serotonin antagonists and non-steroidal anti-inflammatory drugs (NSAIDs). Objectives To assess the effects of pharmacological agents for the prevention of vestibular migraine. Search methods The Cochrane Ear, […]

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Selective serotonin re-uptake inhibitors (SSRIs) for preventing migraine and tension-type headaches

Abstract Background This is an updated version of the Cochrane review published in 2005 on selective serotonin re-uptake inhibitors (SSRIs) for preventing migraine and tension-type headache. The original review has been split in two parts and this review now only regards tension-type headache prevention. Another updated review covers migraine. Tension-type headache is the second most […]

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Feverfew for preventing migraine

Abstract Background This review is an update of a previously published review in the Cochrane Database of Systematic Reviews on ‘Feverfew for preventing migraine’ (2004, Issue 1). Feverfew (Tanacetum parthenium L.) extract is a herbal remedy, which has been used for preventing attacks of migraine. Objectives To systematically review the evidence from double-blind randomised controlled […]

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Caffeine as an analgesic adjuvant for acute pain in adults

Jump to… Abstract Background This is an updated version of the original Cochrane review published in Issue 3, 2012. Caffeine has been added to common analgesics such as paracetamol, ibuprofen, and aspirin, in the belief that it enhances analgesic efficacy. Evidence to support this belief is limited and often based on invalid comparisons. Objectives To […]

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