Headache

Botulinum toxins for the prevention of migraine in adults

Abstract Background Migraine occurs in around 15% of adults and is ranked as the seventh most disabling disease amongst all diseases globally. Despite the available treatments many people suffer prolonged and frequent attacks which have a major impact on their quality of life. Chronic migraine is defined as 15 or more days of headache per […]

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Needle gauge and tip designs for preventing post-dural puncture headache (PDPH)

Abstract Background Post-dural puncture headache (PDPH) is one of the most common complications of diagnostic and therapeutic lumbar punctures. PDPH is defined as any headache occurring after a lumbar puncture that worsens within 15 minutes of sitting or standing and is relieved within 15 minutes of the patient lying down. Researchers have suggested many types […]

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Aspirin for acute treatment of episodic tension-type headache in adults

Abstract Background Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache per month), frequent episodic TTH (two to 14 headache days per month), and chronic TTH (15 headache days per month or more). Aspirin is one of a number of analgesics suggested for […]

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Ketoprofen for episodic tension-type headache in adults

Abstract Background Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache day per month), frequent episodic TTH (2 to 14 headache days per month), and chronic TTH (15 headache days a month or more). Ketoprofen is one of a number of analgesics suggested […]

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Paracetamol (acetaminophen) for acute treatment of episodic tension-type headache in adults

Abstract Background Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache per month), frequent episodic TTH (two to 14 headaches per month), and chronic TTH (15 headache days a month or more). Paracetamol (acetaminophen) is one of a number of analgesics suggested for […]

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Sumatriptan plus naproxen for acute migraine attacks in adults

Abstract Background This is an updated version of the original Cochrane review published in October 2013 on ‘Sumatriptan plus naproxen for acute migraine attacks in adults’. Migraine is a common disabling condition and a burden for the individual, health services, and society. It affects two to three times more women than men, and is most […]

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Drugs for the acute treatment of migraine in children and adolescents

Abstract Background Numerous medications are available for the acute treatment of migraine in adults, and some have now been approved for use in children and adolescents in the ambulatory setting. A systematic review of acute treatment of migraine medication trials in children and adolescents will help clinicians make evidence-informed management choices. Objectives To assess the […]

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Acupuncture for tension-type headache

Abstract Background Acupuncture is often used for prevention of tension-type headache but its effectiveness is still controversial. This is an update of our Cochrane review originally published in Issue 1, 2009 ofThe Cochrane Library. Objectives To investigate whether acupuncture is a) more effective than no prophylactic treatment/routine care only; b) more effective than ‘sham’ (placebo) […]

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Posture and fluids for preventing post-dural puncture headache

Abstract Background Post-dural puncture headache (PDPH) is a common complication of lumbar punctures. Several theories have identified the leakage of cerebrospinal fluid (CSF) through the hole in the dura as a cause of this side effect. It is therefore necessary to take preventive measures to avoid this complication. Prolonged bed rest has been used to […]

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Normobaric and hyperbaric oxygen therapy for migraine and cluster headache

Abstract Background Migraine and cluster headaches are severe and disabling. Migraine affects up to 18% of women, while cluster headaches are much less common (0.2% of the population). A number of acute and prophylactic therapies are available. Hyperbaric oxygen therapy (HBOT) is the therapeutic administration of 100% oxygen at environmental pressures greater than one atmosphere, […]

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