Decompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury

Abstract Background High intracranial pressure (ICP) is the most frequent cause of death and disability after severe traumatic brain injury (TBI). It is usually treated with general maneuvers (normothermia, sedation, etc.) and a set of first‐line therapeutic measures (moderate hypocapnia, mannitol, etc.). When these measures fail, second‐line therapies are initiated, which include: barbiturates, hyperventilation, moderate hypothermia, […]