Spinal cord

High-dose chemotherapy for children and young adults with stage IV rhabdomyosarcoma

Abstract Background Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Prognosis for patients with metastatic disease has not improved significantly in the past decades. High-dose chemotherapy (HDC) seems to be an attractive option to treat minimal residual disease in metastatic rhabdomyosarcoma patients. Objectives The objective of the review was to assess the effectiveness […]

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Interventions for the treatment of metastatic extradural spinal cord compression in adults

Abstract Background Metastatic epidural spinal cord compression (MESCC) is often treated with radiotherapy and corticosteroids. Recent reports suggest benefit from decompressive surgery. Objectives To determine effectiveness and adverse effects of radiotherapy, surgery and corticosteroids in MESCC. Search methods CENTRAL, MEDLINE, EMBASE, CINAHL, LILACS and CANCERLIT were searched; last search ran July 2008 Selection criteria We […]

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