Multiple sclerosis

Aminopyridines for symptomatic treatment in multiple sclerosis

Abstract Background The potassium channel blockers 4-aminopyridine (AP) and 3,4-diaminopyridine (DAP) increase nerve conduction in demyelinated nerve fibers, and have been proposed as a symptomatic therapy for people with multiple sclerosis (MS). Objectives To determine the efficacy and safety of aminopyridines for neurological deficits in adults with MS. Search methods We searched the Cochrane MS […]

Share

Exercise therapy for multiple sclerosis

Abstract Background No intervention has proven effective in modifying long-term disease prognosis in Multiple Sclerosis (MS) but exercise therapy is considered to be an important part of symptomatic and supportive treatment for these patients. Objectives To assess the effectiveness of exercise therapy for patients with MS in terms of activities of daily living and health-related […]

Share

Bladder training for urinary incontinence in adults

Abstract Background Urinary incontinence is a common and distressing problem. Bladder training aims to increase the interval between voids and is widely used for the treatment of urinary incontinence. Objectives To assess the effects of bladder training for the treatment of urinary incontinence. Search methods We searched the Cochrane Incontinence Group Specialised Trials Register (searched […]

Share

Hyperbaric oxygen therapy for multiple sclerosis

Abstract Background Multiple Sclerosis (MS) is a chronic, recurrent and progressive illness with no cure. On the basis of speculative pathophysiology, it has been suggested that Hyperbaric Oxygen Therapy (HBOT) may slow or reverse the progress of the disease. Objectives The object of this review was to evaluate the efficacy and safety of HBOT in […]

Share

Anti-spasticity agents for multiple sclerosis

Abstract Background Spasticity is a common problem in multiple sclerosis (MS) patients causing pain, spasms, loss of function and difficulties in nursing care. A variety of oral and parenteral medications are available. Objectives To assess the absolute and comparative efficacy and tolerability of anti-spasticity agents in MS patients. Search methods We searched the Cochrane MS […]

Share

Occupational therapy for multiple sclerosis

Abstract Background Multiple sclerosis (MS) patients are referred to occupational therapy with complaints about fatigue, limb weakness, alteration of upper extremity fine motor coordination, loss of sensation and spasticity that causes limitations in performance of activities of daily living and social participation. The primary purpose of occupational therapy is to enable individuals to participate in […]

Share

Intravenous immunoglobulins for multiple sclerosis

Abstract Background Animal experiments suggest that intravenous immunoglobulins can reverse some of the disease process of central nervous system demyelination. Subsequently, clinical trials of intravenous immunoglobulins have been conducted in people with multiple sclerosis (MS). Objectives To identify and summarise the evidence that intravenous immunoglobulins are safe and beneficial for people with MS. Search methods […]

Share

Corticosteroids or ACTH for acute exacerbations in multiple sclerosis

Abstract Background Corticosteroids are commonly used to improve the rate of recovery from acute exacerbation in multiple sclerosis (MS) patients. However, it is unclear just how effective these agents are and which is the best treatment schedule (type of drug, dose, frequency, duration of treatment and route of administration). This review is un update of […]

Share

Pharmacotherapy for Behcet’s syndrome

Abstract Background Behcet’s syndrome is a multisystemic disorder presenting with recurrent oral and genital ulcerations as well as ocular involvement. Treatment of Behcet’s syndrome is symptomatic and empirical. Objectives To determine the effects of available pharmacological interventions in treating the different clinical features of Behcet’s syndrome. Search methods We searched the Cochrane Musculoskeletal Group’s trials […]

Share
  • The review abstracts published on this site are the property of John Wiley & Sons, Ltd., and of the Cochrane Review Groups that have produced the reviews.
Share
Share